Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776884 | 0.86 | KCNH2 (0.33) | PLAU | |
| SCHEMBL4509702 | 0.81 | KCNH2 (0.35) | — | |
| SCHEMBL4501354 | 0.79 | KCNH2 (0.43) | — | |
| SCHEMBL4522945 | 0.77 | KCNH2 (0.54) | — | |
| SCHEMBL4507976 | 0.77 | KCNH2 (0.54) | — | |
| SCHEMBL4502729 | 0.71 | KCNH2 (0.52) | — | |
| SCHEMBL4520953 | 0.71 | PLAU (0.33) | PLAU | |
| SCHEMBL4520946 | 0.71 | PLAU (0.33) | PLAU | |
| Hydrochloric Acid SCHEMBL6194315 | 0.67 | KCNH2 (0.40) | — | |
| SCHEMBL4775783 | 0.67 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |