Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL1477531 | 0.97 | TSHR (0.59) | TSHRTTRTDP1ALDH1A1USP2 | |
| Tetrahydrofuran SCHEMBL23711833 | 0.88 | TSHR (0.56) | TSHRTDP1ALDH1A1USP2PKM | |
| Butanol SCHEMBL28313456 | 0.88 | — | — | |
| Dioxane SCHEMBL28118854 | 0.84 | TTR (0.40) | TSHRTTRUSP2SMN1; SMN2 | |
| Morpholine SCHEMBL28604861 | 0.82 | MEN1 (0.50) | TSHRGAAMEN1KMT2A | |
| Dioxane SCHEMBL28127315 | 0.81 | TDP1 (0.62) | TSHRTTRTDP1ALDH1A1USP2 | |
| Oxirane SCHEMBL27471704 | 0.80 | — | — | |
| Dioxane SCHEMBL4414289 | 0.79 | ALDH1A1 (0.50) | TTRALDH1A1USP2MEN1KMT2A | |
| Butanol SCHEMBL55049 | 0.79 | — | — | |
| Butanol SCHEMBL1418 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942892-A1 | SOLID DISPERSIONS OF OPIOID ANTAGONISTS | Adolor Corporation (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007044713-A1 | SOLID DISPERSIONS OF OPIOID ANTAGONISTS | ADOLOR CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |