Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2347036 | 0.99 | DRD2 (0.64) | DRD2DRD3 | |
| SCHEMBL2347632 | 0.96 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL6601712 | 0.92 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL7450768 | 0.88 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL392268 | 0.88 | DRD2 (0.66) | DRD2DRD3 | |
| SCHEMBL8205951 | 0.88 | DRD2 (0.66) | DRD2DRD3 | |
| SCHEMBL16463637 | 0.88 | DRD2 (0.58) | DRD2DRD3 | |
| SCHEMBL2232549 | 0.86 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL6600239 | 0.84 | DRD2 (0.66) | DRD2DRD3 | |
| SCHEMBL16464827 | 0.80 | DRD2 (0.76) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601659-B1 | PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2008-01-16 | — | — | EP | disclosed |
| EP-1601659-A1 | PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | Abbott GmbH & Co. KG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004080981-A1 | PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2004-09-23 | — | — | WO | disclosed |