⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146154 | 1.00 | — | — | |
| SCHEMBL1821046 | 0.97 | — | — | |
| SCHEMBL4444740 | 0.90 | — | — | |
| SCHEMBL5709839 | 0.83 | — | — | |
| SCHEMBL11502069 | 0.83 | CYP2D6 (0.32) | — | |
| SCHEMBL19442063 | 0.73 | CHRNA7 (0.40) | — | |
| SCHEMBL36730 | 0.73 | FDPS (0.38) | — | |
| SCHEMBL2256328 | 0.73 | FDPS (0.38) | — | |
| SCHEMBL21973884 | 0.73 | CHRNA7 (0.40) | — | |
| SCHEMBL9669427 | 0.73 | FDPS (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |