Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 3/20 | 0.35 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437962 | 0.77 | CYP2A6 (0.52) | CYP11B1CYP11B2TP53MAPTALDH1A1 | |
| SCHEMBL13692396 | 0.76 | MKNK1 (0.51) | CYP11B1CYP11B2MAPTBRAFALDH1A1 | |
| SCHEMBL4763109 | 0.74 | MAPT (0.43) | CYP11B1CYP11B2MAPTLMNACYP2C9 | |
| SCHEMBL569420 | 0.71 | CYP2E1 (0.50) | BRAFALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL25171070 | 0.70 | CYP2E1 (0.49) | EPHA2BRAFKMT2AHCKNR2C2 | |
| SCHEMBL31016008 | 0.70 | CYP2E1 (0.49) | EPHA2BRAFKMT2AHCKNR2C2 | |
| SCHEMBL2932508 | 0.70 | CHEK2 (0.58) | CYP11B1CYP11B2BRAFCYP2C9CYP2E1 | |
| SCHEMBL30314856 | 0.70 | CHEK2 (0.58) | CYP11B1CYP11B2BRAFCYP2C9CYP2E1 | |
| SCHEMBL4767563 | 0.70 | LMNA (0.59) | ALDH1A1KMT2ALMNA | |
| SCHEMBL13687505 | 0.70 | CYP2E1 (0.45) | EPHA2BRAFHCKNR2C2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439169-B1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7273878-B2 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | CYP11B1 1170/4885CYP11B2 1399/4885EPHA2 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.