Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672018 | 0.78 | ATM (0.35) | — | |
| SCHEMBL10407764 | 0.72 | — | — | |
| SCHEMBL10883108 | 0.70 | — | — | |
| SCHEMBL1341564 | 0.70 | SGMS2 (0.44) | MEN1KMT2APDE4A | |
| SCHEMBL7573610 | 0.69 | CDK1 (0.32) | — | |
| SCHEMBL27888393 | 0.69 | MAPT (0.39) | KMT2A | |
| SCHEMBL27573366 | 0.67 | KCNN4 (0.41) | — | |
| SCHEMBL1521834 | 0.67 | HDAC8 (0.32) | — | |
| SCHEMBL27888361 | 0.67 | KCNN4 (0.41) | — | |
| SCHEMBL6554119 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |