⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599558 | 0.68 | — | — | |
| SCHEMBL3708618 | 0.65 | — | — | |
| SCHEMBL1429756 | 0.63 | — | — | |
| SCHEMBL323470 | 0.63 | — | — | |
| SCHEMBL6414862 | 0.63 | MEN1 (0.33) | — | |
| SCHEMBL6414470 | 0.63 | MEN1 (0.33) | — | |
| SCHEMBL3648749 | 0.62 | LMNA (0.32) | — | |
| SCHEMBL3651917 | 0.62 | LMNA (0.32) | — | |
| SCHEMBL11040106 | 0.61 | MEN1 (0.31) | — | |
| SCHEMBL793302 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686996-A4 | QUINAZOLINONE COMPOUNDS WITH REDUCED BIOACCUMULATION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-1686996-A1 | QUINAZOLINONE COMPOUNDS WITH REDUCED BIOACCUMULATION | CHIRON CORPORATION (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051391-A1 | QUINAZOLINONE COMPOUNDS WITH REDUCED BIOACCUMULATION | CHIRON CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |