Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127741 | 0.92 | TLR7 (0.53) | TLR7TLR8NUDT1ALPLLMNA | |
| SCHEMBL4142764 | 0.92 | TLR7 (0.60) | TLR7TLR8NUDT1GBA1 | |
| SCHEMBL4122028 | 0.90 | TLR7 (0.48) | TLR7TLR8NUDT1LMNA | |
| SCHEMBL4129216 | 0.88 | TLR7 (0.49) | TLR7TLR8NUDT1ALPLSMN1; SMN2 | |
| SCHEMBL5068477 | 0.87 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL18166856 | 0.87 | TLR7 (0.44) | TLR7TLR8NUDT1ACKR3LMNA | |
| SCHEMBL4710315 | 0.86 | TLR7 (0.52) | TLR7TLR8NUDT1KMT2A | |
| SCHEMBL4122208 | 0.85 | TLR7 (0.48) | TLR7TLR8NUDT1ALPLSMN1; SMN2 | |
| SCHEMBL4124564 | 0.85 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL3895075 | 0.85 | TLR7 (0.48) | TLR7TLR8NUDT1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874345-A4 | IMMUNOSTIMULATORY COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1874345-A2 | IMMUNOSTIMULATORY COMPOSITIONS | 3M Innovative Properties Company (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006116475-A2 | IMMUNOSTIMULATORY COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-11-02 | — | — | WO | disclosed |