SCHEMBL4127741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5068477	0.95	TLR7 (0.51)	TLR7TLR8NUDT1
	SCHEMBL4769814	0.92	TLR7 (0.52)	TLR7TLR8NUDT1LMNAALPL
	SCHEMBL4142764	0.89	TLR7 (0.60)	TLR7TLR8NUDT1
	SCHEMBL4129216	0.89	TLR7 (0.49)	TLR7TLR8NUDT1LMNAALPL
	SCHEMBL4122028	0.87	TLR7 (0.48)	TLR7TLR8NUDT1LMNA
	SCHEMBL4134187	0.87	TLR7 (0.69)	TLR7TLR8NUDT1
	SCHEMBL4122208	0.86	TLR7 (0.48)	TLR7TLR8NUDT1HDAC6LMNA
	SCHEMBL18166856	0.83	TLR7 (0.44)	TLR7TLR8NUDT1HDAC6LMNA
	SCHEMBL4124564	0.83	TLR7 (0.49)	TLR7TLR8NUDT1HDAC6
	SCHEMBL3895075	0.83	TLR7 (0.48)	TLR7TLR8NUDT1HDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.