SCHEMBL4769866

SCHEMBL4769866

Cn1ccc2ncnc(Oc3cc[c]c(Cl)c3)c21

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDR P35968 20/20 0.51
FGFR1 P11362 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4764330 0.82 KDR (0.57) KDR
SCHEMBL4284980 0.77 KDR (0.56) KDRFGFR1
SCHEMBL29186532 0.75 KDR (0.53) KDR
SCHEMBL4287177 0.74 KDR (0.60) KDR
SCHEMBL4762561 0.73 KDR (0.47) KDR
SCHEMBL4286007 0.73 KDR (0.51) KDR
SCHEMBL19223052 0.72 KDR (0.69) KDR
SCHEMBL4278057 0.72 KDR (0.60) KDR
SCHEMBL4285896 0.72 KDR (0.51) KDR
SCHEMBL4287792 0.71 KDR (0.51) KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904498-A1 FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2008-04-02 EP disclosed
WO-2007004749-A1 FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-01-11 WO disclosed