Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791785 | 0.86 | APEX1 (0.57) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1143449 | 0.82 | APEX1 (0.54) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL27521981 | 0.79 | APEX1 (0.51) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL16279612 | 0.79 | APEX1 (0.51) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL4771465 | 0.78 | L3MBTL1 (0.48) | KMT2AKDM4EALDH1A1L3MBTL1TDP1 | |
| SCHEMBL28829127 | 0.78 | APEX1 (0.45) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7376159 | 0.74 | KMT2A (0.59) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6942194 | 0.74 | KMT2A (0.59) | APEX1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL4748257 | 0.73 | NPC1 (0.51) | APEX1KMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL11406769 | 0.73 | APEX1 (0.56) | APEX1KMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172049-B | Method for preparing furan-2, 5-dimethyl diformate by oxidizing and esterifying 5-hydroxymethylfurfural | 中国科学院大连化学物理研究所 | 2021-01-05 | — | — | CN | disclosed |
| CN-110172049-A | The method that 5 hydroxymethyl furfural oxidative esterification prepares dehydromucic acid dimethyl ester | 中国科学院大连化学物理研究所 | 2019-08-27 | — | — | CN | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| EP-1874749-A1 | FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114272-A1 | FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | APEX1 1636/4885KMT2A 3116/4885MEN1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.