Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.51 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4768548 | 0.93 | ALDH1A1 (0.64) | ALDH1A1LMNAHRH3DHX9MAPT | |
| SCHEMBL4770289 | 0.84 | HRH3 (0.51) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL4772665 | 0.83 | HRH3 (0.52) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL4765905 | 0.82 | NPC1 (0.69) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL4768020 | 0.82 | SLC2A1 (0.53) | ALDH1A1LMNAHRH3MAPTCREBBP | |
| SCHEMBL4768220 | 0.82 | HRH3 (0.49) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL4774583 | 0.82 | HRH3 (0.57) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL6299537 | 0.82 | ALDH1A1 (0.76) | ALDH1A1LMNADHX9MAPT | |
| SCHEMBL4770276 | 0.82 | HRH3 (0.49) | ALDH1A1LMNAHRH3MAPTRAB9A | |
| SCHEMBL4767467 | 0.81 | HRH3 (0.50) | ALDH1A1LMNAHRH3MAPTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |