Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768540 | 0.91 | CCR5 (0.75) | CCR5KCNH2 | |
| SCHEMBL4768594 | 0.88 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4773958 | 0.87 | CCR5 (0.81) | CCR5KCNH2 | |
| SCHEMBL4777027 | 0.86 | CCR5 (0.83) | CCR5KCNH2 | |
| SCHEMBL4775650 | 0.84 | CCR5 (0.80) | CCR5KCNH2 | |
| SCHEMBL4775171 | 0.84 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4775616 | 0.83 | CCR5 (0.78) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL4771685 | 0.83 | CCR5 (0.98) | CCR5KCNH2 | |
| SCHEMBL4768104 | 0.83 | CCR5 (0.74) | CCR5KCNH2 | |
| SCHEMBL4777222 | 0.82 | CCR5 (1.00) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348324-B2 | Cyclic amine compounds as CCR5 antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-25 | — | — | US | disclosed |
| EP-1886994-A1 | Cyclic amine compounds as CCR5 antagonists | Takeda Pharmaceutical Company Limited (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-6562978-B1 | N-(3-(4-(4-(Aminocarbonyl)benzyl)-1-piperidinyl)propyl)-N-(3, 4-dichlorophenyl)-1-(methylsulfonyl)-4-piperidinecarboxamide or a salt thereof for treatment of AIDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-05-13 | — | — | US | disclosed |