Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780371 | 0.80 | HSP90AA1 (0.39) | MARS1MEN1KMT2AFASNCYP1A2 | |
| SCHEMBL4771806 | 0.78 | ESRRA (0.40) | MARS1RAD51MAPTRAB9ARXFP1 | |
| SCHEMBL4778866 | 0.75 | CHRNA7 (0.42) | MARS1MEN1TP53HPGDKMT2A | |
| SCHEMBL4778476 | 0.72 | TP53 (0.43) | MARS1MEN1TP53HPGDKMT2A | |
| SCHEMBL12325069 | 0.72 | HSP90AA1 (0.56) | MAPTRAB9AMEN1HPGDKMT2A | |
| SCHEMBL4779727 | 0.70 | TP53 (0.41) | MARS1MAPTRAB9AMEN1TP53 | |
| SCHEMBL28303202 | 0.70 | ESR2 (0.57) | MAPTRAB9AMEN1TP53ALOX12 | |
| SCHEMBL9732916 | 0.70 | CYP2A6 (0.50) | MAPTRAB9AMEN1TP53HPGD | |
| SCHEMBL4779710 | 0.70 | TP53 (0.39) | MARS1MEN1TP53HPGDKMT2A | |
| SCHEMBL31265226 | 0.67 | GSK3B (0.48) | MAPTRAB9AMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | claimed |
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | disclosed |