SCHEMBL477186

SCHEMBL477186

CN1CC2CNCC2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17057342 1.00
SCHEMBL1394033 1.00
SCHEMBL25960786 1.00
SCHEMBL18636553 1.00
SCHEMBL12457734 1.00
Hydrochloric Acid SCHEMBL31566713 0.97 CHRNB2 (0.46)
Hydrochloric Acid SCHEMBL7850055 0.97 CHRNB2 (0.46)
Hydrochloric Acid SCHEMBL27195898 0.97 CHRNB2 (0.46)
Hydrochloric Acid SCHEMBL7850056 0.97 CHRNB2 (0.46)
Hydrochloric Acid SCHEMBL15058446 0.97 CHRNB2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110248939-A tyrosine amide derivatives as RHO-kinase inhibitors 奇斯药制品公司 2019-09-17 CN claimed
CN-106661019-A Indolizine derivatives as phoshoinositide 3-kinases inhibitors 奇斯药制品公司 2017-05-10 CN claimed
WO-2026107208-A1 COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS THE METHODIST HOSPITAL (US) 2026-05-21 WO disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-12485169-B2 Compounds Grey Wolf Therapeutics Limited (GB) 2025-12-02 US disclosed
WO-2025242908-A2 NOVEL COMPOUNDS GENOME THERAPEUTICS LTD (GB) 2025-11-27 WO disclosed
WO-2025133338-A1 QUINOLONE DERIVATVES AGAINST CANCER GENOME THERAPEUTICS LTD (GB) 2025-06-26 WO disclosed
WO-2025125302-A1 NOVEL COMPOUNDS GENOME THERAPEUTICS LTD (GB) 2025-06-19 WO disclosed
CN-115916771-B Multi-target antitumor compound and preparation method and application thereof 浙江华海药业股份有限公司 2025-04-01 CN disclosed
US-20250101052-A1 COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION, AND USE THEREOF INNOVATION INSTITUTE FOR ARTIFICIAL INTELLIGENCE IN MEDICINE OF ZHEJIANG UNIVERSITY (CN) 2025-03-27 US disclosed
EP-4522154-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-03-19 EP disclosed
EP-0523512-B1 8-vinyl- and 8-ethinyl-quinolone carboxylic acids BAYER AG (DE) 1997-01-15 EP disclosed
US-5578604-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5545642-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-08-13 US disclosed
US-5468742-A Antibacterial agents, feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
EP-0671391-A1 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids BAYER AG (DE) 1995-09-13 EP disclosed
EP-0653425-A1 1-(2-Fluorocyclopropyl)-quinolone- and naphthyridone carboxylic acid derivatives, their preparation and their use as antibacterials BAYER AG (DE) 1995-05-17 EP disclosed
EP-0523512-A1 8-vinyl- and 8-ethinyl-quinolone carboxylic acids BAYER AG (DE) 1993-01-20 EP disclosed
US-5179090-A Antiischemic agents; treatment of asthma, bronchitis, heart diseases DR. KARL THOMAE GMBH (DE) 1993-01-12 US disclosed
EP-0417630-A2 Condensed diazepinones, process for their preparation, and medicaments containing these compounds Dr. Karl Thomae GmbH (DE) 1991-03-20 EP disclosed