Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 12/20 | 0.44 |
| ▸ | RAB9A | P51151 | 12/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768190 | 0.77 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL4774316 | 0.75 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL4775079 | 0.75 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL4772782 | 0.75 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL4771412 | 0.74 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4777033 | 0.74 | HRH3 (0.39) | HRH3JAK2JAK3PTK2 | |
| SCHEMBL4774290 | 0.73 | HRH3 (0.50) | NPC1RAB9AMEN1KMT2AHRH3 | |
| SCHEMBL4770984 | 0.73 | RORC (0.54) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL5459684 | 0.72 | HRH3 (0.53) | NPC1RAB9AMEN1KMT2AHRH3 | |
| SCHEMBL4774168 | 0.72 | HRH3 (0.53) | NPC1RAB9AMEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | BTK 3106/4885NPC1 2009/4885RAB9A 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.