Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 2/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585877 | 0.90 | CENPE (0.72) | CENPES1PR1S1PR3SUV39H2 | |
| SCHEMBL2105023 | 0.90 | CENPE (0.72) | CENPES1PR1S1PR3SUV39H2 | |
| SCHEMBL2103138 | 0.83 | CENPE (0.71) | CENPES1PR1S1PR3ALDH1A1 | |
| SCHEMBL13456913 | 0.82 | CENPE (0.56) | CENPES1PR1S1PR3ALDH1A1HPGD | |
| SCHEMBL13183953 | 0.81 | CENPE (0.57) | CENPEALDH1A1HPGDSUV39H2NPC1 | |
| SCHEMBL3461323 | 0.80 | CENPE (0.79) | CENPES1PR1S1PR3ALDH1A1HPGD | |
| SCHEMBL13161841 | 0.80 | CENPE (0.79) | CENPES1PR1S1PR3ALDH1A1HPGD | |
| SCHEMBL10274283 | 0.78 | CENPE (0.52) | CENPES1PR1S1PR3ALDH1A1HPGD | |
| SCHEMBL3461358 | 0.77 | CENPE (0.83) | CENPES1PR1S1PR3ALDH1A1HPGD | |
| SCHEMBL2105698 | 0.77 | CENPE (0.83) | CENPES1PR1S1PR3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742907-A4 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1742907-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005107762-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2005-11-17 | — | — | WO | disclosed |