⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193923 | 0.82 | — | — | |
| SCHEMBL11252741 | 0.79 | — | — | |
| SCHEMBL4721891 | 0.79 | — | — | |
| SCHEMBL3505790 | 0.78 | — | — | |
| SCHEMBL945322 | 0.78 | — | — | |
| SCHEMBL6585669 | 0.78 | GBA1 (0.35) | — | |
| SCHEMBL2279540 | 0.75 | — | — | |
| SCHEMBL1462392 | 0.75 | — | — | |
| SCHEMBL946962 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL1384272 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092764-A1 | KINASE INHIBITORS | INSILICO MEDICINE IP LIMITED (HK) | 2024-03-21 | — | — | US | claimed |
| US-20240092765-A1 | METHODS OF INHIBITING KINASES | INSILICO MEDICINE IP LIMITED (HK) | 2024-03-21 | — | — | US | claimed |
| US-20240018154-A1 | NEW INDAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2024-01-18 | — | — | US | claimed |
| US-11795160-B2 | Kinase inhibitors | INSILICO MEDICINE IP LIMITED (HK) | 2023-10-24 | — | — | US | claimed |
| EP-4255906-A1 | NEW INDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-11 | — | — | EP | claimed |
| US-11739078-B2 | Methods of inhibiting kinases | INSILICO MEDICINE IP LIMITED (HK) | 2023-08-29 | — | — | US | claimed |
| CN-114805438-A | Phosphoacyl-containing TYK2 inhibitor compounds | 正大天晴药业集团股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| WO-2022117487-A1 | NEW INDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-09 | — | — | WO | claimed |
| CN-113924295-A | Kinase inhibitors | 英矽智能科技知识产权有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-113861144-A | Griseofulvin ring-opening derivative and preparation method thereof | 南通大学 | 2021-12-31 | — | — | CN | claimed |
| WO-2001004083-A1 | COVALENT DERIVATIVES OF ALKANOLAMIDES OF MONOCARBOXYLIC AND DICARBOXYLIC ACIDS FUNCTIONALLY ACTIVE ON THE CB2 CANNABINOID RECEPTOR | INNOVET ITALIA S.R.L. (IT) | 2001-01-18 | — | — | WO | claimed |
| EP-0675169-B1 | Cationic thiadiazole dyes | BAYER AG (DE) | 1998-09-16 | — | — | EP | claimed |
| EP-0816351-A1 | Functional N-vinylformamides, process for their preparation and their use in free radical polymerisation reactions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-01-07 | — | — | EP | claimed |
| US-5580964-A | USED FOR DYEING AND PRINTING PAPER IN LIGHTFAST SHADES, AS DICHROIC DYES FOR POLARIZING FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | claimed |
| EP-0675169-A2 | Cationic thiadiazole dyes | BAYER AG (DE) | 1995-10-04 | — | — | EP | claimed |
| EP-0417555-B1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0076199-B1 | TRIAZOLOQUINAZOLONES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR PREPARING THEM, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-12-30 | — | — | EP | claimed |
| US-4472400-A | Triazoloquinazolones having antihistaminic and bronchospasmolytic activity | ROUSSEL UCLAF (FR) | 1984-09-18 | — | — | US | claimed |
| EP-0076199-A2 | Triazoloquinazolones and their salts, process and intermediates for preparing them, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1983-04-06 | — | — | EP | claimed |
| US-3933823-A | CNS DEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-20 | — | — | US | claimed |