Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239522 | 0.91 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL11510046 | 0.89 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28483095 | 0.81 | TSHR (0.45) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11139404 | 0.80 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28340198 | 0.80 | THRB (0.45) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27785353 | 0.79 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL27979674 | 0.78 | THRB (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11203323 | 0.76 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Trimethylammonium SCHEMBL4974909 | 0.76 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28820020 | 0.75 | TSHR (0.49) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999294-A2 | PROCESS FOR PREPARING SUBSTRATES WITH POROUS SURFACE | Advanced Materials Technology, Inc. (US) | 2008-12-10 | — | — | EP | claimed |
| WO-2007095158-A2 | PROCESS FOR PREPARING SUBSTRATES WITH POROUS SURFACE | ADVANCED MATERIALS TECHNOLOGY, INC. (US) | 2007-08-23 | — | — | WO | claimed |
| EP-1999294-A2 | PROCESS FOR PREPARING SUBSTRATES WITH POROUS SURFACE | Advanced Materials Technology, Inc. (US) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007095158-A2 | PROCESS FOR PREPARING SUBSTRATES WITH POROUS SURFACE | ADVANCED MATERIALS TECHNOLOGY, INC. (US) | 2007-08-23 | — | — | WO | disclosed |
| US-4158595-A | AQUEOUS SUSPENSION OF ANIONIC AND CATIONIC NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-06-19 | — | — | US | disclosed |
| US-4154647-A | TREATMENT WITH AQUEOUS MIXTURE OF CATIONIC AND ANIONIC WATER-SOLUBLE NITROGEN-CONTAINING POLYMERS | HERCULES INCORPORATED (US) | 1979-05-15 | — | — | US | disclosed |