Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167160 | 0.96 | GPR119 (0.53) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL4172068 | 0.96 | GPR119 (0.53) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL4172065 | 0.96 | GPR119 (0.53) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL16390912 | 0.91 | GPR119 (0.51) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL16390913 | 0.91 | GPR119 (0.51) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL2454639 | 0.81 | POLB (0.71) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL31050717 | 0.81 | POLB (0.71) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL2454638 | 0.81 | POLB (0.71) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL20989256 | 0.81 | CHRM2 (0.55) | CHRM2CHRM1CHRM3GPR119ALDH1A1 | |
| SCHEMBL21526582 | 0.81 | CHRM2 (0.55) | CHRM2CHRM1CHRM3GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987042-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | sanofi-aventis (FR) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093365-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |