Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021223 | 0.94 | KMT2A (0.42) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4021226 | 0.94 | KMT2A (0.42) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4028149 | 0.90 | MEN1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4028145 | 0.90 | MEN1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4028188 | 0.90 | MEN1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4023694 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4021972 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4021968 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4022026 | 0.83 | MEN1 (0.45) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4020222 | 0.83 | MAPT (0.39) | MEN1KMT2AMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |