Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519430 | 0.96 | CCR5 (0.52) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4771713 | 0.83 | CCR5 (0.57) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4775602 | 0.78 | CCR5 (0.67) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4773937 | 0.78 | CCR5 (0.67) | CCR5 | |
| SCHEMBL4776629 | 0.77 | CCR5 (0.70) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4777499 | 0.74 | CCR5 (0.68) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4773813 | 0.73 | CCR5 (0.73) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4771362 | 0.73 | CCR5 (0.63) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL5120067 | 0.73 | CCR5 (0.63) | CCR5 | |
| SCHEMBL4773808 | 0.72 | CCR5 (0.66) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886994-A1 | Cyclic amine compounds as CCR5 antagonists | Takeda Pharmaceutical Company Limited (JP) | 2008-02-13 | — | — | EP | disclosed |