Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171033 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1KDM4E | |
| SCHEMBL27481210 | 0.81 | CNR1 (0.57) | KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7239606 | 0.81 | ATM (0.43) | SLC6A1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5394384 | 0.80 | CNR1 (0.56) | KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL27528272 | 0.76 | KMT2A (0.44) | SLC6A1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1964502 | 0.76 | CYP1A2 (0.62) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL30363975 | 0.76 | OPRM1 (0.61) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL30364119 | 0.76 | OPRM1 (0.61) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL8916036 | 0.76 | CYP1A2 (0.62) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL1894379 | 0.75 | KDM4E (0.44) | KMT2AOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907372-A1 | SUBSTITUTED CYCLOHEXYL DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003965-A1 | SUBSTITUTED CYCLOHEXYL DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |