Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28410804 | 0.98 | TAAR1 (0.54) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL28789463 | 0.86 | TAAR1 (0.52) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL3640948 | 0.80 | DPP4 (0.62) | TAAR1HTR2ADPP4F2CHRNB2 | |
| SCHEMBL16496872 | 0.78 | TACR1 (0.50) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL2126865 | 0.78 | TACR1 (0.50) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL2126869 | 0.78 | TACR1 (0.50) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL29006641 | 0.78 | HRH1 (0.63) | TAAR1HTR2ATACR1DPP4F2 | |
| SCHEMBL156218 | 0.76 | SLC6A2 (0.61) | TAAR1HTR2ADPP4SLC6A2SLC6A4 | |
| SCHEMBL3927827 | 0.76 | TAAR1 (0.58) | TAAR1HTR2ADPP4F2CHRNB2 | |
| SCHEMBL5872302 | 0.76 | TACR1 (0.58) | TAAR1TACR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164526-A | 2- (piperazine-2-yl) acetonitrile derivative, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| WO-2023226900-A1 | 2-(PIPERAZINE-2-YL) ACETONITRILE DERIVATIVE, PREPARATION METHOD FOR, AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-11-30 | — | — | WO | claimed |
| CN-117043216-A | Adducts of alkylated diamines with novolak epoxy resins | SIKA技术股份公司 | 2023-11-10 | — | — | CN | claimed |
| CN-114634818-B | Benzyl Gemini surfactant and preparation method thereof | 福州大学 | 2023-01-10 | — | — | CN | claimed |
| CN-114634818-A | Benzyl Gemini surfactant and preparation method thereof | 福州大学 | 2022-06-17 | — | — | CN | claimed |
| CN-118121552-A | Injectable pharmaceutical composition and preparation method and application thereof | 浙江萃泽医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-110869346-B | Inhibitors of plasminogen activator inhibitor-1 (PAI-1) and methods of use | 密歇根大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| CN-112673042-B | Accelerators for curing epoxy resins containing alkylated amines | SIKA技术股份公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117164526-A | 2- (piperazine-2-yl) acetonitrile derivative, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023226900-A1 | 2-(PIPERAZINE-2-YL) ACETONITRILE DERIVATIVE, PREPARATION METHOD FOR, AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-115844838-B | Injectable pharmaceutical composition | 浙江萃泽医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112789308-B | Curing agent for epoxy resins | SIKA技术股份公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| CN-1419448-A | Remedies | TAKARA BIO INC (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1404829-A | Double inhibitor synthesized by wax ester and cholesterol ester for inbibiting generation of sebum | WARNER LAMBERT CO (US) | 2003-03-26 | — | — | CN | disclosed |
| CN-1376161-A | Novel bicyclic nucleoside analogues | SANKYO CO (JP) | 2002-10-23 | — | — | CN | disclosed |
| CN-1370079-A | Remedies for skin ulcer | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | CN | disclosed |
| CN-1347418-A | Novel nucleosides and oligonucleotide analogues | SANKYO CO (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1284878-A | Drugs augmenting NKT cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-02-21 | — | — | CN | disclosed |
| CN-1226555-A | Antifungal agent, and preparation method and intermediate thereof | — | 1999-08-25 | — | — | CN | disclosed |