Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22614679 | 1.00 | ROCK2 (0.52) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL31344399 | 1.00 | ROCK2 (0.52) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL4779691 | 1.00 | ROCK2 (0.52) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL31344396 | 1.00 | ROCK2 (0.52) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| Beta-Alanine SCHEMBL21194018 | 0.92 | ROCK2 (0.47) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL28782549 | 0.88 | ROCK2 (0.50) | ROCK2ALDH1A1CYP2C9CYP2C19HPGD | |
| SCHEMBL6366679 | 0.84 | CYP2C9 (0.49) | ALDH1A1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL1863359 | 0.84 | CYP2C9 (0.49) | ALDH1A1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL6366676 | 0.84 | CYP2C9 (0.49) | ALDH1A1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL6743921 | 0.83 | CYP2C9 (0.59) | ALDH1A1CYP2C9CYP2C19HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | claimed |
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | disclosed |