Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863697 | 0.98 | POLB (0.44) | EPHX2POLBKDM4EMAPK1HIF1A | |
| SCHEMBL146344 | 0.94 | ALDH1A1 (0.46) | EPHX2POLBKDM4EMAPK1HIF1A | |
| SCHEMBL145975 | 0.85 | KDM4D (0.39) | POLBKDM4EKMT2AALDH1A1CA2 | |
| SCHEMBL27160294 | 0.83 | EPHX2 (0.52) | EPHX2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL14739515 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 | |
| SCHEMBL14739265 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 | |
| SCHEMBL14739816 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 | |
| SCHEMBL14740061 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 | |
| SCHEMBL14739086 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 | |
| SCHEMBL15836237 | 0.82 | GRIA1 (0.52) | EPHX2POLBKDM4EALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831221-A4 | SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831221-A2 | SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS | 3M Innovative Properties Company (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006083440-A2 | SUBSTITUTED CHIRAL FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |