SCHEMBL4773740

SCHEMBL4773740

CC1CC=C2C(C)(C)CCC[C@@]2(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
CACNA1G O43497 1/20 0.37
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4942302 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3152488 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3151569 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3156464 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3146268 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3155245 1.00 ACHE (0.39) ACHECACNA1GCYP19A1
SCHEMBL3155271 0.76 CYP19A1 (0.31) CYP19A1
SCHEMBL3155361 0.76 CYP19A1 (0.31) CYP19A1
SCHEMBL3155358 0.76 CYP19A1 (0.31) CYP19A1
SCHEMBL3152155 0.70 ACHE (0.41) ACHECACNA1GCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910262-A1 NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS FIRMENICH SA (CH) 2008-04-16 EP disclosed
WO-2007010420-A1 NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS FIRMENICH SA (CH) 2007-01-25 WO disclosed