Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705804 | 0.89 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CF2RL1S1PR1 | |
| SCHEMBL698117 | 0.86 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL698495 | 0.83 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL1573502 | 0.81 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL697032 | 0.79 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL697142 | 0.78 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CF2RL1FPR2 | |
| SCHEMBL696169 | 0.75 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL697119 | 0.74 | NISCH (0.52) | ADRA2AADRA2BADRA2CF2RL1NISCH | |
| SCHEMBL698494 | 0.72 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CF2RL1FPR2 | |
| SCHEMBL1573281 | 0.72 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CF2RL1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | Pfizer Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007083207-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |