Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.74 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.68 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | F3 | P13726 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225611 | 0.92 | MAOB (0.71) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL27846176 | 0.92 | MAPT (0.73) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL27846178 | 0.92 | MAPT (0.73) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL1225612 | 0.92 | MAOB (0.71) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL11696308 | 0.88 | MAOB (0.74) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL11696311 | 0.88 | MAOB (0.74) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL28622228 | 0.85 | MAOB (1.00) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL30383266 | 0.84 | TNFRSF1A (1.00) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL3215700 | 0.84 | TNFRSF1A (1.00) | MAOBTNFRSF1AMAPTLMNAHPGD | |
| SCHEMBL7198201 | 0.84 | TNFRSF1A (0.74) | MAOBTNFRSF1AMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2008006626-A1 | TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | FREIE UNIVERSITÄT BERLIN (DE) | 2008-01-17 | — | — | WO | disclosed |