Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.74 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | F3 | P13726 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17370988 | 0.93 | CTSL (0.64) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL3215707 | 0.85 | TNFRSF1A (1.00) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL4139154 | 0.85 | GABRA3 (0.78) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL3215700 | 0.85 | TNFRSF1A (1.00) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL28339980 | 0.85 | GABRA3 (0.78) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL30383266 | 0.85 | TNFRSF1A (1.00) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL30674925 | 0.85 | TNFRSF1A (1.00) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL4773932 | 0.84 | MAOB (0.74) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL4774104 | 0.84 | MAOB (0.74) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 | |
| SCHEMBL29264653 | 0.83 | TNFRSF1A (0.56) | TNFRSF1AGABRA3GABRA2GABRB2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599921-B2 | Antiproliferative agents against estrogen-dependent cancer cells dibenzothiopyran, dibenzopyran and phenanthrene derivatives | NANODESIGN, INC. (CA) | 2003-07-29 | — | — | US | disclosed |
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | PALOMA PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002066428-A2 | NON-STEROIDAL ESTROGEN RECEPTOR LIGANDS | NANODESIGN INC. (CA) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156077-A1 | Non-steroidal estrogen receptor ligands | ESRRA, ESRRB, ESRRG | TNFRSF1A 105/4885GABRA3 531/4885GABRA2 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.