Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774283 | 0.85 | HRH3 (0.43) | HRH3CYP2D6KDM2BHRH1 | |
| SCHEMBL4767950 | 0.85 | HRH3 (0.48) | HRH3CYP2D6KDM2BHRH1 | |
| SCHEMBL4770408 | 0.82 | HRH3 (0.43) | HRH3CYP2D6KDM2B | |
| SCHEMBL4765539 | 0.81 | HRH3 (0.62) | HRH3CYP2D6HRH1 | |
| SCHEMBL4775429 | 0.81 | KDM2B (0.42) | HRH3CYP2D6KDM2B | |
| SCHEMBL4770829 | 0.80 | HRH3 (0.45) | HRH3CYP2D6KDM2BHRH1 | |
| SCHEMBL4771920 | 0.78 | HRH3 (0.42) | HRH3CYP2D6KDM2B | |
| SCHEMBL4775800 | 0.78 | FKBP1A (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL4770278 | 0.78 | HRH3 (0.60) | HRH3CYP2D6HRH1 | |
| Trifluoroacetic Acid SCHEMBL4772701 | 0.75 | SLC2A1 (0.52) | HRH3KDM2BMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | HRH3 1/4885CYP2D6 1672/4885KDM2B 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.