Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168284 | 0.85 | SMN1; SMN2 (0.42) | CA12CA14CA2CA1KMT2A | |
| SCHEMBL3738506 | 0.82 | DGAT1 (0.39) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL1794611 | 0.82 | DGAT1 (0.39) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL1794608 | 0.82 | DGAT1 (0.39) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL4477961 | 0.82 | CA1 (0.42) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL3693114 | 0.80 | CA12 (0.38) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL3693112 | 0.80 | CA12 (0.38) | CA12CA14DGAT1CA2CA1 | |
| Ammonia Solution, Strong SCHEMBL28795834 | 0.80 | CA12 (0.38) | CA12CA14DGAT1CA2CA1 | |
| Ammonia Solution, Strong SCHEMBL27983360 | 0.80 | CA12 (0.38) | CA12CA14DGAT1CA2CA1 | |
| SCHEMBL20241539 | 0.79 | CA12 (0.35) | CA12CA14DGAT1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | claimed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | claimed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | claimed |