Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.59 |
| ▸ | NPC1 | O15118 | 14/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4771045 | 0.92 | RAB9A (0.53) | RAB9ANPC1PKMHPGDNFKB1 | |
| SCHEMBL4768108 | 0.91 | NPC1 (0.51) | RAB9ANPC1PKMHPGDNFKB1 | |
| SCHEMBL4765305 | 0.91 | RAB9A (0.48) | RAB9ANPC1PKMHPGDNFKB1 | |
| Hydrochloric Acid SCHEMBL4774495 | 0.90 | RAB9A (0.47) | RAB9ANPC1PKMHPGDNFKB1 | |
| Hydrochloric Acid SCHEMBL4776625 | 0.90 | NPC1 (0.50) | RAB9ANPC1PKMHPGDNFKB1 | |
| SCHEMBL4772163 | 0.89 | NPC1 (0.57) | RAB9ANPC1PKMPOLBKMT2A | |
| SCHEMBL4768367 | 0.89 | NPC1 (0.48) | RAB9ANPC1PKMHPGDNFKB1 | |
| Hydrochloric Acid SCHEMBL4770710 | 0.88 | NPC1 (0.47) | RAB9ANPC1PKMHPGDNFKB1 | |
| SCHEMBL4765359 | 0.88 | NPC1 (0.44) | RAB9ANPC1PKMNFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL4772031 | 0.87 | NPC1 (0.43) | RAB9ANPC1PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |