Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774623 | 0.73 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9540684 | 0.72 | SLC33A1 (0.39) | — | |
| SCHEMBL9541039 | 0.71 | SLC33A1 (0.39) | — | |
| SCHEMBL9848892 | 0.71 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9422505 | 0.70 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9552841 | 0.70 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL9553146 | 0.69 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9848931 | 0.69 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9848912 | 0.69 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL6961100 | 0.69 | NPC1 (0.39) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877067-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONE GLUCURONIDE DERIVATIVES FOR HYPERCHOLESTEROLEMIA | Microbia, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006116499-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONE GLUCURONIDE DERIVATIVES FOR HYPERCHOLESTEROLEMIA | MICROBIA, INC. (US) | 2006-11-02 | — | — | WO | disclosed |