Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179930 | 0.93 | ALDH1A1 (0.41) | CSNK1DALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL14653211 | 0.86 | PLAT (0.39) | ALDH1A1KDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL14653348 | 0.86 | ALDH1A1 (0.37) | CSNK1DSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL20976610 | 0.85 | ALDH1A1 (0.42) | CSNK1DALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL14653271 | 0.83 | ALDH1A1 (0.46) | CSNK1DSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL12180283 | 0.77 | PDE10A (0.54) | ALDH1A1KDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL2047911 | 0.77 | PDE10A (0.47) | CSNK1DALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27869897 | 0.77 | CHRM3 (0.46) | — | |
| SCHEMBL4428463 | 0.75 | PDE10A (0.45) | — | |
| SCHEMBL26984291 | 0.74 | CSNK1D (0.58) | CSNK1DSMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |