Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774745 | 1.00 | TRPV1 (0.53) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4768005 | 0.94 | TRPV1 (0.51) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4767993 | 0.94 | TRPV1 (0.51) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4773031 | 0.89 | TRPV1 (0.53) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4773020 | 0.89 | TRPV1 (0.53) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4765707 | 0.89 | IMPDH2 (0.57) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4765698 | 0.89 | IMPDH2 (0.57) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4767400 | 0.87 | MAPT (0.57) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4767410 | 0.87 | MAPT (0.57) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4774472 | 0.86 | TRPV1 (0.50) | TRPV1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |