P-Methoxy-Acetophenone

P-Methoxy-Acetophenone

SCHEMBL4774856

COc1ccc(C(=O)C=Cc2ccc(OC)cc2F)cc1.COc1ccc(C(C)=O)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.67
TNFRSF1A P19438 1/20 0.65
GABRA3 P34903 1/20 0.61
GABRA2 P47869 1/20 0.61
GABRB2 P47870 1/20 0.61
MCL1 Q07820 1/20 0.60
ABCG2 Q9UNQ0 1/20 0.59
MAPT P10636 3/20 0.56
LMNA P02545 2/20 0.56
HPGD P15428 1/20 0.56
CYP1A1 P04798 1/20 0.56
CYP1B1 Q16678 1/20 0.56
NPC1 O15118 1/20 0.55
ALDH1A1 P00352 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CYP3A4 P08684 1/20 0.55
CDC25A P30304 1/20 0.55
CDC25C P30307 1/20 0.55
F3 P13726 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4774104 0.95 MAOB (0.74) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL27846203 0.86 MAPT (0.73) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL27846201 0.86 MAPT (0.73) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL29090933 0.82 CYP1A1 (0.58) MAOBTNFRSF1AABCG2MAPTLMNA
SCHEMBL5479178 0.81 MAOB (1.00) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL5479175 0.81 MAOB (1.00) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL1390301 0.80 MAOB (0.55) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL5915590 0.80 MAOB (0.55) MAOBTNFRSF1AGABRA3GABRA2GABRB2
SCHEMBL5915902 0.80 MAOB (0.55) MAOBTNFRSF1AGABRA3GABRA2GABRB2
P-Methoxy-Acetophenone SCHEMBL4774853 0.80 MEN1 (0.65) MAOBTNFRSF1AABCG2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008006626-A1 TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS FREIE UNIVERSITÄT BERLIN (DE) 2008-01-17 WO disclosed