Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | APP | P05067 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | F3 | P13726 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774099 | 0.92 | MEN1 (0.74) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25205853 | 0.89 | APP (0.75) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL27903981 | 0.82 | F3 (0.87) | MEN1KMT2ALMNAALDH1A1ABCG2 | |
| SCHEMBL27975130 | 0.82 | F3 (0.87) | MEN1KMT2ALMNAALDH1A1ABCG2 | |
| SCHEMBL25196696 | 0.81 | MEN1 (0.63) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL7198195 | 0.80 | ABCG2 (0.74) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| P-Methoxy-Acetophenone SCHEMBL4774856 | 0.80 | MAOB (0.67) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25214779 | 0.79 | MEN1 (1.00) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25214812 | 0.79 | MEN1 (1.00) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL9420980 | 0.79 | MAPT (0.72) | MEN1KMT2ALMNAALDH1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006626-A1 | TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | FREIE UNIVERSITÄT BERLIN (DE) | 2008-01-17 | — | — | WO | disclosed |