SCHEMBL4775241

SCHEMBL4775241

CCOC(=O)C=Cc1ccccc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.67
ALDH1A1 P00352 6/20 0.67
HPGD P15428 4/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
NFE2L2 Q16236 2/20 0.67
TFEB P19484 1/20 0.66
MAPT P10636 5/20 0.61
KMT2A Q03164 4/20 0.61
LMNA P02545 3/20 0.60
MEN1 O00255 3/20 0.60
PLIN1 O60240 1/20 0.60
POLB P06746 1/20 0.60
PLIN5 Q00G26 1/20 0.60
ABHD5 Q8WTS1 1/20 0.60
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
BCHE P06276 1/20 0.59
NPSR1 Q6W5P4 2/20 0.57
MAPK1 P28482 1/20 0.57
ATM Q13315 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15188 1.00 KDM4E (0.67) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL13957562 1.00 KDM4E (0.67) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL31506312 1.00 KDM4E (0.67) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL1205800 0.91 MAPT (0.61) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL1205797 0.91 MAPT (0.61) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL16852753 0.89 KDM4E (0.55) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL2474892 0.88 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244433 0.88 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL3536947 0.88 SMN1; SMN2 (0.60) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL3536949 0.88 SMN1; SMN2 (0.60) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528981-A Chiral phosphonate compound and derivative thereof, preparation method, pesticide bacteriostat and application 贵州大学 2025-02-28 CN claimed
CN-119528981-A Chiral phosphonate compound and derivative thereof, preparation method, pesticide bacteriostat and application 贵州大学 2025-02-28 CN disclosed
CN-116023202-A Synthetic method of alpha-chlorarone derivative 西南大学 2023-04-28 CN disclosed
CN-112851624-A Synthetic method of 2-benzoxazepine compound 云南大学 2021-05-28 CN disclosed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP disclosed
US-7462713-B2 Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy AGOURON PHARMACEUTICALS, INC. (US) 2008-12-09 US disclosed
US-7462713-B2 Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy AGOURON PHARMACEUTICALS, INC. (US) 2008-12-09 US disclosed
WO-2004063198-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2004-07-29 WO disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0190496-A2 Piperidine derivatives having a gastro-intestinal activity BEECHAM GROUP PLC (GB) 1986-08-13 EP disclosed
US-3987176-A COMPOSITION AND USE OF 3,4-DIHYDROPYRIDONES AS VASODILATORS AND ANTIHYPERTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-19 US disclosed
US-3981882-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed
US-3951990-A CORONARY AGENTS, HYPOTENSIVE BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed
US-3951992-A CORONARY, HYPOTENSIVE BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed
US-3951991-A CORONARY AGENTS, HYPOTENSIVE BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed