SCHEMBL2474892

SCHEMBL2474892

CCCOC(=O)/C=C/c1ccccc1OC

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.72
ALDH1A1 P00352 7/20 0.72
HPGD P15428 5/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
NFE2L2 Q16236 2/20 0.63
TFEB P19484 1/20 0.62
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
MAPT P10636 4/20 0.58
ALOX5 P09917 1/20 0.58
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
LMNA P02545 2/20 0.56
BCHE P06276 1/20 0.56
AKR1B10 O60218 3/20 0.55
AKR1B1 P15121 3/20 0.55
MAPK1 P28482 1/20 0.55
ATM Q13315 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19244433 1.00 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL1614877 0.92 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244312 0.92 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL5177689 0.92 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL466048 0.90 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL4629237 0.90 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872479 0.90 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872224 0.90 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL4421062 0.90 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244471 0.90 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP disclosed
EP-2370398-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE KAO CORPORATION, S.A. (ES) 2011-10-05 EP disclosed
WO-2010072810-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE KAO CORPORATION, S.A. (ES) 2010-07-01 WO disclosed
WO-2006072175-A1 SKIN CARE COMPOSITIONS HABER DERMACEUTICS INC. (CA) 2006-07-13 WO disclosed