Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055398 | 0.81 | CYP1A2 (0.48) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL27289193 | 0.81 | ERN1 (0.52) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11309867 | 0.79 | PADI4 (0.53) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL5841529 | 0.79 | ERN1 (0.44) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL5843386 | 0.79 | ERN1 (0.58) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL14877209 | 0.78 | ALDH1A1 (0.43) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL10978821 | 0.77 | CYP2A6 (0.46) | CYP1A2MAPTCYP2A6TDP1ALDH1A1 | |
| SCHEMBL342278 | 0.76 | ERN1 (0.57) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29388184 | 0.76 | ERN1 (0.57) | ERN1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL1666535 | 0.76 | CYP1A2 (0.50) | ERN1CYP1A2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |