SCHEMBL4775381 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MAOB	P27338	5/20	0.43

▸	MAOA	P21397	2/20	0.43

▸	ADORA1	P30542	10/20	0.41

▸	ADORA2A	P29274	10/20	0.41

▸	ALOX5AP	P20292	2/20	0.40

▸	FEN1	P39748	2/20	0.40

▸	ATR	Q13535	1/20	0.35

▸	IKBKB	O14920	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4113347	0.92	MAOB (0.45)	MAOBMAOAADORA1ADORA2AALOX5AP
SCHEMBL4775383	0.88	MAOB (0.38)	MAOBMAOAADORA1ADORA2AALOX5AP
SCHEMBL4101040	0.85	ADORA2A (0.44)	MAOBMAOAADORA1ADORA2A
SCHEMBL4110202	0.85	ADORA1 (0.51)	ADORA1ADORA2AATR
SCHEMBL4107496	0.78	DCPS (0.48)	MAOBADORA2A
SCHEMBL4096455	0.77	MAOB (0.49)	MAOBMAOAADORA1ADORA2A
SCHEMBL4108022	0.76	MAOB (0.44)	MAOBMAOAALOX5APFEN1
SCHEMBL4107477	0.75	ADORA2A (0.49)	ADORA1ADORA2AATR
SCHEMBL4102014	0.74	MAOB (0.44)	MAOBMAOAADORA1ADORA2AALOX5AP
SCHEMBL4097472	0.74	ADORA2A (0.53)	ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008009076-A2	SUBSTITUTED PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING VIRAL INFECTIONS	GILEAD SCIENCES, INC. (US)	2008-01-24	—	—	WO	claimed