Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7186874 | 0.99 | CCR3 (0.53) | CCR3HTR2ACCR5 | |
| Hydrochloric Acid SCHEMBL6056734 | 0.99 | CCR3 (0.53) | CCR3HTR2ACCR5 | |
| SCHEMBL4777958 | 0.93 | CCR5 (0.49) | CCR3CCR5 | |
| Hydrochloric Acid SCHEMBL7185877 | 0.92 | CCR5 (0.48) | CCR3CCR5 | |
| SCHEMBL4770891 | 0.91 | CCR3 (0.54) | CCR3HTR2A | |
| Hydrochloric Acid SCHEMBL7192828 | 0.90 | CCR3 (0.53) | CCR3HTR2A | |
| SCHEMBL4775599 | 0.90 | TMEM97 (0.60) | CCR3 | |
| Hydrochloric Acid SCHEMBL6056639 | 0.89 | TMEM97 (0.59) | CCR3 | |
| Hydrochloric Acid SCHEMBL7187539 | 0.89 | TMEM97 (0.59) | CCR3 | |
| SCHEMBL4776592 | 0.87 | CCR3 (0.57) | CCR3HTR2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348324-B2 | Cyclic amine compounds as CCR5 antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-25 | — | — | US | disclosed |
| EP-1886994-A1 | Cyclic amine compounds as CCR5 antagonists | Takeda Pharmaceutical Company Limited (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-20030114443-A1 | Cyclic amine compounds as CCR5 antagonists | TOBIRA THERAPEUTICS, INC. | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114443-A1 | Cyclic amine compounds as CCR5 antagonists | CCR5, CCR1, CCR3 | CCR3 3/4885HTR2A 629/4885CCR5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.