Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.63 |
| ▸ | KDR | P35968 | 6/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.63 |
| ▸ | ABL1 | P00519 | 2/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | LYN | P07948 | 2/20 | 0.63 |
| ▸ | RET | P07949 | 2/20 | 0.63 |
| ▸ | HCK | P08631 | 2/20 | 0.63 |
| ▸ | BCR | P11274 | 2/20 | 0.63 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.63 |
| ▸ | FLT3 | P36888 | 2/20 | 0.63 |
| ▸ | ABL2 | P42684 | 2/20 | 0.63 |
| ▸ | FRK | P42685 | 2/20 | 0.63 |
| ▸ | MST1R | Q04912 | 2/20 | 0.63 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.63 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.63 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.63 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.63 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555863 | 0.90 | MET (0.61) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL2258237 | 0.90 | MET (0.72) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL2254725 | 0.90 | KDR (0.78) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL3559220 | 0.88 | MET (0.57) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL3561525 | 0.86 | MET (0.59) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL3560402 | 0.86 | MET (0.58) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL13038449 | 0.86 | MET (0.58) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL3556875 | 0.86 | MET (0.58) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL2252979 | 0.85 | KDR (0.73) | METKDRNTRK1RIPK2ABL1 | |
| SCHEMBL2249552 | 0.85 | KDR (0.73) | METKDRNTRK1RIPK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889836-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) | Eisai R&D Management Co., Ltd. (JP) | 2008-02-20 | — | — | EP | disclosed |