Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471773 | 1.00 | TRPA1 (0.57) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL9782402 | 1.00 | TRPA1 (0.57) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL10928526 | 1.00 | TRPA1 (0.57) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL8935462 | 0.98 | TRPA1 (0.54) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL8849468 | 0.91 | HDAC3 (0.50) | TRPA1MAPTRXFP1SIGMAR1MAOA | |
| SCHEMBL19682101 | 0.87 | TRPA1 (0.67) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL598212 | 0.84 | TDP1 (0.55) | — | |
| SCHEMBL10037075 | 0.83 | TRPA1 (0.54) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL5793873 | 0.83 | S1PR2 (0.57) | TRPA1MAPTRXFP1SIGMAR1S1PR2 | |
| SCHEMBL4590802 | 0.83 | TRPA1 (0.54) | TRPA1MAPTRXFP1SIGMAR1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197051-B | Compound and preparation method and application thereof | 中国药科大学 | 2023-11-03 | — | — | CN | disclosed |
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2008080832-A2 | CARBONITRIDES AS CATALYSTS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-07-10 | — | — | WO | disclosed |
| EP-1941946-A1 | Carbonitrides as catalysts | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-07-09 | — | — | EP | disclosed |