Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794442 | 0.90 | MCHR1 (0.53) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL1734148 | 0.90 | BRD4 (0.47) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL13605326 | 0.85 | MCHR1 (0.55) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL1735408 | 0.84 | BRD4 (0.46) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL13605312 | 0.81 | BRD4 (0.46) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL13605345 | 0.80 | BRD4 (0.47) | BRD4JAK1HDAC1JAK2RET | |
| SCHEMBL13605342 | 0.80 | KCNH2 (0.47) | LTA4HBRD4JAK1HDAC1JAK2 | |
| SCHEMBL13605367 | 0.79 | HRH3 (0.44) | LTA4HBRD4JAK1HDAC1JAK2 | |
| SCHEMBL1735235 | 0.79 | LTA4H (0.52) | MCHR1LTA4HBRD4JAK1HDAC1 | |
| SCHEMBL13605354 | 0.78 | BRD4 (0.56) | BRD4JAK1HDAC1JAK2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038669-A9 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC | 2008-05-29 | — | — | WO | claimed |