SCHEMBL4775932

SCHEMBL4775932

CCCCCCCCC([O])C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.46
PPARD Q03181 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
OPRM1 P35372 1/20 0.46
ADH1B P00325 1/20 0.45
ADH1C P00326 1/20 0.45
ADH1A P07327 1/20 0.45
ADH4 P08319 1/20 0.45
ADH7 P40394 1/20 0.45
ACE2 Q9BYF1 1/20 0.43
GPR84 Q9NQS5 3/20 0.43
FDPS P14324 3/20 0.43
SPHK1 Q9NYA1 1/20 0.43
FFAR1 O14842 1/20 0.43
CA1 P00915 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3971199 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL5048400 0.97 OPRM1 (0.48) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL4398732 0.89
SCHEMBL11740428 0.84 LCK (0.46) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL7077831 0.83 LCK (0.48) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL8374215 0.82 LCK (0.50) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL5512232 0.80 OPRM1 (0.52) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL5509935 0.80 OPRM1 (0.52) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL8372235 0.80 LCK (0.43) LCKPPARDZDHHC20ZDHHC2OPRM1
SCHEMBL10436241 0.80 LCK (0.43) LCKPPARDZDHHC20ZDHHC2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080064736-A1 Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides BAYER CROPSCIENCE AG (DE) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064736-A1 Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides DDT, PPM1F, PPM1D LCK 3940/4885PPARD 598/4885ZDHHC20 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.