Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775896 | 0.92 | KCNH2 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL4776256 | 0.88 | KCNH2 (0.40) | KCNH2KCNQ1CACNA1CSLC2A1 | |
| SCHEMBL4515145 | 0.82 | KCNH2 (0.63) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4521791 | 0.81 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL4522581 | 0.80 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4515650 | 0.73 | KCNH2 (0.63) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4506334 | 0.72 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL4512974 | 0.72 | KCNH2 (0.72) | KCNH2SLC2A1 | |
| SCHEMBL4774053 | 0.71 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4508624 | 0.71 | KCNH2 (0.45) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |