SCHEMBL4776402

SCHEMBL4776402

Cc1ccccc1C(c1ccccc1)(c1ccccc1C)N(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.64
TSHR P16473 3/20 0.36
ACHE P22303 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
KIF11 P52732 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRK1 P41145 1/20 0.33
KCNH2 Q12809 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
GABRA1 P14867 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5921941 0.79 KCNN4 (1.00) KCNN4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL7879108 0.79 KCNN4 (0.42) KCNN4TSHRACHEMEN1KMT2A
SCHEMBL6556714 0.73 KCNN4 (0.61) KCNN4TSHRCRHBPCRHR2MEN1
SCHEMBL9632116 0.73 TSHR (0.43) KCNN4TSHRACHEMEN1LMNA
SCHEMBL27820283 0.71 TSHR (0.41) KCNN4TSHRACHEGABRA1GABRB2
SCHEMBL4109393 0.71 TSHR (0.41) KCNN4TSHRACHELMNAKIF11
SCHEMBL3400019 0.71 ESR1 (0.48) KCNN4TSHRACHEMAPTKMT2A
SCHEMBL2780246 0.71 KCNN4 (0.46) KCNN4TSHRACHEMAPTKMT2A
SCHEMBL27918575 0.71 ESR1 (0.48) KCNN4TSHRACHEMAPTKMT2A
SCHEMBL9421204 0.71 ESR1 (0.46) KCNN4TSHRACHEMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911111-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, EXPOSURE DEVICE AND IMAGE FORMING APPARATUS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-04-16 EP disclosed
US-20070063639-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, EXPOSURE DEVICE AND IMAGE FORMING MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-03-22 US disclosed
WO-2007013692-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, EXPOSURE DEVICE AND IMAGE FORMING APPARATUS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-02-01 WO disclosed
WO-2005006460-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND AN EXPOSURE UNIT AND IMAGE-FORMING APPARATUS BOTH USING THE ELEMENT MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-20 WO disclosed