SCHEMBL7879108

SCHEMBL7879108

CCN(CC)C(c1ccccc1)(c1ccccc1C)c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.42
KIF11 P52732 1/20 0.35
CHRM3 P20309 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPY2R P49146 1/20 0.33
TSHR P16473 2/20 0.32
ACHE P22303 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745740 0.82 KCNN4 (0.54) KCNN4CHRM3CHRM2CHRM1SIGMAR1
SCHEMBL4776402 0.79 KCNN4 (0.64) KCNN4KIF11KMT2AMEN1CYP2D6
SCHEMBL3190702 0.75 KCNN4 (0.39) KCNN4SIGMAR1KMT2AMEN1CYP2D6
SCHEMBL3739354 0.73 MAPT (0.35) KMT2ATSHRACHEALDH1A1MAPK1
SCHEMBL295495 0.73 ACHE (0.35) KIF11KMT2AMEN1TSHRACHE
SCHEMBL15577796 0.72 KCNN4 (0.43) KCNN4KIF11SIGMAR1ALDH1A1TAAR1
SCHEMBL15398955 0.69 KIF11 (0.49) KCNN4KIF11KCNH2
SCHEMBL3049242 0.69 KCNN4 (0.43) KCNN4CHRM3CHRM2CHRM1SIGMAR1
SCHEMBL5967520 0.69 KCNN4 (0.54) KCNN4CHRM3CHRM2CHRM1SIGMAR1
SCHEMBL9632116 0.69 TSHR (0.43) KCNN4KIF11KMT2AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174638-B1 EXCELLENT SOLUBILITY IN AN ORGANIC SOLVENT, EXCELLENT COMPATIBILITY WITH A RESIN BINDER AND EXCELLENT PHOTOSENSITIVITY; USEFUL AS AN ELECTRON-TRANSPORTING AGENT FOR THE PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY KYOCERA MITA CORPORATION (JP) 2001-01-16 US disclosed
EP-0745903-B1 Process for preparing a multilayer electrophotographic imaging member XEROX CORP (US) 2000-10-18 EP disclosed
US-5856013-A CHARGE TRANSPORT LAYER AND A FLUORINATED CARBON FILLED FLUOROELASTOMER LAYER. XEROX CORPORATION 1999-01-05 US disclosed
EP-0745903-A1 Process for preparing a multilayer electrophotographic imaging member XEROX CORPORATION (US) 1996-12-04 EP disclosed
EP-0239353-B1 FABRICATION OF SEAMLESS SUBSTRATES XEROX CORPORATION (US) 1993-06-23 EP disclosed
US-5116703-A Functional hybrid compounds and thin films by sol-gel process XEROX CORPORATION (US) 1992-05-26 US disclosed
EP-0145400-B1 PHOTOCONDUCTIVE DEVICES CONTAINING NOVEL SQUARAINE COMPOUNDS XEROX CORPORATION (US) 1991-05-29 EP disclosed
EP-0146301-B1 PROCESS FOR SYNTHESIZING SQUARAINE COMPOSITIONS XEROX CORPORATION (US) 1988-07-13 EP disclosed
US-4711833-A Powder coating process for seamless substrates XEROX CORPORATION (US) 1987-12-08 US disclosed
EP-0102850-B1 LAYERED PHOTORESPONSIVE DEVICE XEROX CORPORATION (US) 1987-05-20 EP disclosed
EP-0145400-A2 Photoconductive devices containing novel squaraine compounds XEROX CORPORATION (US) 1985-06-19 EP disclosed
EP-0144195-A2 Squaraine compositions XEROX CORPORATION (US) 1985-06-12 EP disclosed
US-4486520-A Photoconductive devices containing novel squaraine compositions XEROX CORPORATION (US) 1984-12-04 US disclosed
US-4471041-A Photoconductive devices containing novel squaraine compositions XEROX CORPORATION (US) 1984-09-11 US disclosed
EP-0102850-A1 Layered photoresponsive device XEROX CORPORATION (US) 1984-03-14 EP disclosed
US-4413899-A Copying method and apparatus RICOH COMPANY, LTD. (JP) 1983-11-08 US disclosed
EP-0077217-A1 Layered organic photoresponsive device XEROX CORPORATION (US) 1983-04-20 EP disclosed
US-4275132-A ELECTROGRAPHIC CARBON BLACK OR GRAPHITE DISPERSED IN A POLYMER SPECIFICALLY A POLYESTER XEROX CORPORATION (US) 1981-06-23 US disclosed
US-4275133-A Electrophotographic imaging processes utilizing adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1981-06-23 US disclosed
US-4251612-A CARBON OR GRAPHITE DISPERSED IN POLYMER, HOLE INJECTING MATERIAL, HOLE TRANSPORT LAYER XEROX CORPORATION (US) 1981-02-17 US disclosed